Group-sequential analysis may allow for early trial termination: illustration by an intra-observer repeatability study

Abstract Background Group-sequential testing is widely used in pivotal therapeutic, but rarely in diagnostic research, although it may save studies, time, and costs. The purpose of this paper was to demonstrate a group-sequential analysis strategy in an intra-observer study on quantitative FDG-PET/C...

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Bibliographic Details
Main Authors: Oke Gerke, Mie H. Vilstrup, Ulrich Halekoh, Malene Grubbe Hildebrandt, Poul Flemming Høilund-Carlsen
Format: Article
Language:English
Published: SpringerOpen 2017-09-01
Series:EJNMMI Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13550-017-0328-6