Protective effects of heme oxygenase-1 against severe acute pancreatitis via inhibition of tumor necrosis factor-α and augmentation of interleukin-10

Protective effects of heme oxygenase-1 against severe acute pancreatitis via inhibition of tumor necrosis factor-α and augmentation of interleukin-10

Abstract Background Heme oxygenase-1 (HO-1) is an inducible defense gene which plays a significant role in inflammation. HO-1 protects cells and tissues through the mechanism of anti-oxidation, maintaining microcirculation and anti-inflammation. The aim of the current study is to investigate the rol...

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Bibliographic Details
Main Authors: Fei-hu Zhang, Yu-han Sun, Kai-liang Fan, Xiao-bin Dong, Ning Han, Hao Zhao, Li Kong
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Gastroenterology
Subjects:
Heme oxygenase-1
Severe acute pancreatitis
Oxidative stress
Tumor necrosis factor-α
Interleukin-10
Online Access:http://link.springer.com/article/10.1186/s12876-017-0651-4

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