No Association of PTGDR −441C/T Polymorphism with Asthma in a North Indian Population

No Association of PTGDR −441C/T Polymorphism with Asthma in a North Indian Population

Background: Asthma is the most prevalent disease in India according to the national survey conducted by NFHS 2 in 1998–399. Prostaglandin D2 (PGD2) is a bronchoconstriction inducing metabolite of arachidonic acid in the mast cells, which is produced on exposure to allergens and acts as a ligand for...

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Main Authors: Niti Birbian, Jagtar Singh, Surinder Kumar Jindal, Amit Joshi, Navneet Batra
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2011-0850
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spelling doaj-9a2c748968884ead892a45c41e9b63a52020-11-24T23:03:33ZengHindawi LimitedDisease Markers0278-02401875-86302011-01-0131635335910.3233/DMA-2011-0850No Association of PTGDR −441C/T Polymorphism with Asthma in a North Indian PopulationNiti Birbian0Jagtar Singh1Surinder Kumar Jindal2Amit Joshi3Navneet Batra4Department of Biotechnology, Panjab University, Chandigarh, IndiaDepartment of Biotechnology, Panjab University, Chandigarh, IndiaDepartment of Pulmonary Medicine, PGIMER, Chandigarh, IndiaDepartment of Biotechnology, S.G.G.S. College, Chandigarh, IndiaDepartment of Biotechnology, G.G.D.S.D. College, Chandigarh, IndiaBackground: Asthma is the most prevalent disease in India according to the national survey conducted by NFHS 2 in 1998–399. Prostaglandin D2 (PGD2) is a bronchoconstriction inducing metabolite of arachidonic acid in the mast cells, which is produced on exposure to allergens and acts as a ligand for the Prostaglandin D2 Receptor (PTGDR). Polymorphisms in the PTGDR gene have been suggested to be involved in the mechanism of asthma.http://dx.doi.org/10.3233/DMA-2011-0850
collection DOAJ
language English
format Article
sources DOAJ
author Niti Birbian
Jagtar Singh
Surinder Kumar Jindal
Amit Joshi
Navneet Batra
spellingShingle Niti Birbian
Jagtar Singh
Surinder Kumar Jindal
Amit Joshi
Navneet Batra
No Association of PTGDR −441C/T Polymorphism with Asthma in a North Indian Population
Disease Markers
author_facet Niti Birbian
Jagtar Singh
Surinder Kumar Jindal
Amit Joshi
Navneet Batra
author_sort Niti Birbian
title No Association of PTGDR −441C/T Polymorphism with Asthma in a North Indian Population
title_short No Association of PTGDR −441C/T Polymorphism with Asthma in a North Indian Population
title_full No Association of PTGDR −441C/T Polymorphism with Asthma in a North Indian Population
title_fullStr No Association of PTGDR −441C/T Polymorphism with Asthma in a North Indian Population
title_full_unstemmed No Association of PTGDR −441C/T Polymorphism with Asthma in a North Indian Population
title_sort no association of ptgdr −441c/t polymorphism with asthma in a north indian population
publisher Hindawi Limited
series Disease Markers
issn 0278-0240
1875-8630
publishDate 2011-01-01
description Background: Asthma is the most prevalent disease in India according to the national survey conducted by NFHS 2 in 1998–399. Prostaglandin D2 (PGD2) is a bronchoconstriction inducing metabolite of arachidonic acid in the mast cells, which is produced on exposure to allergens and acts as a ligand for the Prostaglandin D2 Receptor (PTGDR). Polymorphisms in the PTGDR gene have been suggested to be involved in the mechanism of asthma.
url http://dx.doi.org/10.3233/DMA-2011-0850
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AT jagtarsingh noassociationofptgdr441ctpolymorphismwithasthmainanorthindianpopulation
AT surinderkumarjindal noassociationofptgdr441ctpolymorphismwithasthmainanorthindianpopulation
AT amitjoshi noassociationofptgdr441ctpolymorphismwithasthmainanorthindianpopulation
AT navneetbatra noassociationofptgdr441ctpolymorphismwithasthmainanorthindianpopulation
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