Pan-histone deacetylase inhibitors regulate signaling pathways involved in proliferative and pro-inflammatory mechanisms in H9c2 cells

<p>Abstract</p> <p>Background</p> <p>We have shown previously that pan-HDAC inhibitors (HDACIs) m-carboxycinnamic acid bis-hydroxamide (CBHA) and trichostatin A (TSA) attenuated cardiac hypertrophy in BALB/c mice by inducing hyper-acetylation of cardiac chromatin that w...

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Bibliographic Details
Main Authors: Majumdar Gipsy, Adris Piyatilake, Bhargava Neha, Chen Hao, Raghow Rajendra
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Genomics
Subjects:
Online Access:http://www.biomedcentral.com/1471-2164/13/709