Donepezil increases resistance to induced seizures in a mouse model of Dravet syndrome

Abstract De novo loss‐of‐function mutations in SCN1A are the main cause of Dravet syndrome, a catastrophic encephalopathy characterized by recurrent early‐life febrile seizures, a number of other afebrile seizure types that are often refractory to treatment, and behavioral abnormalities including so...

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Bibliographic Details
Main Authors: Jennifer C. Wong, Jacquelyn T. Thelin, Andrew Escayg
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.50848