Interactions between fatty acids and α-synuclein
α-Synuclein (αS) is an amyloidogenic neuronal protein associated with several neurodegenerative disorders. Although unstructured in solution, αS forms α-helices in the presence of negatively charged lipid surfaces. Moreover, αS was shown to interact with FAs in a manner that promotes protein aggrega...
Main Authors: | Christian Luäcke, Donald L. Gantz, Elena Klimtchuk, James A. Hamilton |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2006-08-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520331564 |
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