The Genetics of Leber’s Hereditary Optic Neuropathy: A Literature Review
Leber’s hereditary optic neuropathy (LHON) is a mitochondrial disease characterized by a painless, acute loss of central vision, with 95% of affected individuals harbouring one of three pathogenic mutations (G11778GA, G3460A, or T14484C). The purpose of this review is to highlight the distinguishin...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of Ottawa
2018-11-01
|
| Series: | University of Ottawa Journal of Medicine |
| Subjects: | |
| Online Access: | https://uottawa.scholarsportal.info/ottawa/index.php/uojm-jmuo/article/view/3846 |