A novel method for the description of voltage-gated ionic currents based on action potential clamp results - Application to hippocampal mossy fiber boutons

Action potential clamp (AP-clamp) recordings of the delayed rectifier K+ current IK and the fast-activated Na+ current INa in rat hippocampal mossy fiber boutons (MFBs) are analyzed using a computational technique recently reported. The method is implemented using a digitized AP from an MFB and com...

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Bibliographic Details
Main Author: John R Clay
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00514/full