Regulatory T cell activity and signs of T cell unresponsiveness in bovine paratuberculosis

Regulatory T cell activity and signs of T cell unresponsiveness in bovine paratuberculosis

Johne’s disease, caused by infection with Mycobacterium avium subspecies paratuberculosis (MAP), is a wasting disease of ruminants displaying a long subclinical stage of infection followed by clinical disease characterized by severe diarrhea, wasting, and premature death. Immunologically, subclinica...

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Bibliographic Details
Main Authors: Jonathan A Roussey, Juan eSteibel, Paul M Coussens
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Veterinary Science
Subjects:
Paratuberculosis
Regulatory T Cell
Treg
Johne’s
T cell unresponsiveness
Online Access:http://journal.frontiersin.org/Journal/10.3389/fvets.2014.00020/full

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