Management and short-term outcomes of neonates born to mothers with active perinatal SARS-CoV-2 infection

Abstract Objective We report here on the management and outcomes of neonates born to mothers with active perinatal SARS-CoV-2 infection. Study design In this prospective study, eligible neonates were enrolled in a database to track in-hospital outcomes and followed up outpatient periodically till 2 ...

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Bibliographic Details
Main Authors: Vineet Lamba, Joan Lien, Jay Desai, Ajay J. Talati
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Pediatrics
Online Access:https://doi.org/10.1186/s12887-021-02872-0
Description
Summary:Abstract Objective We report here on the management and outcomes of neonates born to mothers with active perinatal SARS-CoV-2 infection. Study design In this prospective study, eligible neonates were enrolled in a database to track in-hospital outcomes and followed up outpatient periodically till 2 months of age to assess for late onset symptoms of infection. Results From April 2020 to February 2021, 67 mothers with perinatal SARS-CoV-2 infection and 70 at-risk neonates were included. Two neonates (3%) tested positive for SARS-CoV-2 within 48 h of life but remained asymptomatic during hospitalization and at all follow-up periods. Three infants were reported to have a febrile illness in 2 months follow up period, none of which was attributable to SARS-CoV-2. Conclusion Our data supports the emerging evidence which describes a probable low risk of vertical transmission of SARS-CoV-2. We also demonstrate a low risk of post-natal transmission or late-onset symptomatic infection with SARS-CoV-2.
ISSN:1471-2431