Oral Administration of Shark Type II Collagen Suppresses Complete Freund’s Adjuvant-Induced Rheumatoid Arthritis in Rats

Oral Administration of Shark Type II Collagen Suppresses Complete Freund’s Adjuvant-Induced Rheumatoid Arthritis in Rats

Objective: Shark type II collagen (SCII) is extracted as a glycoprotein from the cartilage of blue shark (Prionace glauca). We aim to confirm the effects of oral tolerance of SCII on inflammatory and immune responses to the ankle joint of rheumatoid-arthritis rats induced by Complete Freund’s Adjuva...

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Bibliographic Details
Main Authors: Wenhui Wu, Jing Xie, Nanping Wang, Bin Bao, Lijuan Chen
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Pharmaceuticals
Subjects:
shark type II collagen
rheumatoid arthritis
oral tolerance
Online Access:http://www.mdpi.com/1424-8247/5/4/339/

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