Prognostic relevance of Wnt-inhibitory factor-1 (<it>WIF1</it>) and Dickkopf-3 (<it>DKK3</it>) promoter methylation in human breast cancer

Prognostic relevance of Wnt-inhibitory factor-1 (<it>WIF1</it>) and Dickkopf-3 (<it>DKK3</it>) promoter methylation in human breast cancer

<p>Abstract</p> <p>Background</p> <p>Secreted Wnt signaling antagonists have recently been described as frequent targets of epigenetic inactivation in human tumor entities. Since gene silencing of certain Wnt antagonists was found to be correlated with adverse patient s...

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Bibliographic Details
Main Authors: Hartmann Arndt, Schüffler Peter J, Fuchs Thomas, Wild Peter J, Veeck Jürgen, Knüchel Ruth, Dahl Edgar
Format: Article
Language:English
Published: BMC 2009-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/217

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