Epithelial cell adhesion molecule (EpCAM) is involved in prostate cancer chemotherapy/radiotherapy response in vivo

Epithelial cell adhesion molecule (EpCAM) is involved in prostate cancer chemotherapy/radiotherapy response in vivo

Abstract Background Development of chemo−/radioresistance is a major challenge for the current prostate cancer (CaP) therapy. We have previously demonstrated that epithelial cell adhesion molecule (EpCAM) is associated with CaP growth and therapeutic resistance in vitro, however, the role of EpCAM i...

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Bibliographic Details
Main Authors: Jie Ni, Paul Cozzi, Julia Beretov, Wei Duan, Joseph Bucci, Peter Graham, Yong Li
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cancer
Subjects:
EpCAM
Prostate cancer
Animal model
PI3K/Akt/mTOR signaling pathway
Chemoresistance
Radioresistance
Online Access:http://link.springer.com/article/10.1186/s12885-018-5010-5

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http://link.springer.com/article/10.1186/s12885-018-5010-5

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