The synthesis, characterization and biological evaluation of a new nitric oxide donor agent

The synthesis of a new xanthine nitric oxide donor (TSP-81) has been discussed. The designed compound includes two structural moieties - theophylline (1,3-dimethylxanthine) and acetaminophen (4-hydroxyacetanilide) linked by the nitric oxide donor alkyl chain as a spacer. The compound has...

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Bibliographic Details
Main Authors: Profire Lenuta, Apotrosoaei Maria, Oprea Anca, Brebu Mihai, Lupascu Florentina, Lupusoru Elena Catalina, Vasile Cornelia
Format: Article
Language:English
Published: Serbian Chemical Society 2014-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2014/0352-51391300131P.pdf