Strategies to Enhance the Efficacy of T-Cell Therapy for Central Nervous System Tumors

Strategies to Enhance the Efficacy of T-Cell Therapy for Central Nervous System Tumors

Mortality rates in patients diagnosed with central nervous system (CNS) tumors, originating in the brain or spinal cord, continue to remain high despite the advances in multimodal treatment regimens, including surgery, radiation, and chemotherapy. Recent success of adoptive cell transfer immunothera...

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Bibliographic Details
Main Authors: Deepak Upreti, David Bakhshinyan, Darin Bloemberg, Parvez Vora, Chitra Venugopal, Sheila K. Singh
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
central nervous system tumors
CART
immune system
glioblastoma
T cells therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.599253/full

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