Toxicological characteristics of dental gel ‘Matripin’

We performed toxicological evaluation of dental gel ‘Matripin.’ Objective: to assess acute and chronic toxicity of dental gel ‘Matripin’ on mature rats. Animals were kept in standard vivarium conditions. Our findings suggest that ‘Matripin’ is a class 5 drug (virtually non-toxic substance). The asse...

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Bibliographic Details
Main Authors: L. I. Arystan, M. A. Romanova, D. Dzh. Kauzbaeva, S. T. Tuleutaeva, D. S. Tutay
Format: Article
Language:Russian
Published: Private institution educational organization of higher education "Medical University "ReaViz" 2020-11-01
Series:Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
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Online Access:https://vestnik.reaviz.ru/jour/article/view/4
Description
Summary:We performed toxicological evaluation of dental gel ‘Matripin.’ Objective: to assess acute and chronic toxicity of dental gel ‘Matripin’ on mature rats. Animals were kept in standard vivarium conditions. Our findings suggest that ‘Matripin’ is a class 5 drug (virtually non-toxic substance). The assessment of chronic toxicity demonstrated that topical application of ‘Matripin’ does not have any toxic effects on the lungs, heart, spleen, liver, and kidneys, since morphological changes in these organs were similar in the experimental and control groups.
ISSN:2226-762X
2782-1579