Microwave assisted synthesis of some new coumarin-pyrazoline hybrids and their antimicrobial activity

A series of pyrazolines 4a-g have been synthesized by Michael addition of chalcones 3a-g with hydrazine hydrate in presence of sodium acetate under conventional heating and microwave irradiation. Structures of the newly synthesized chalcones 3a-g and pyrazolines 4a-g have been established o...

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Main Authors:	Ashok Dongamanti, Lakshmi Bommidi Vijaya, Ravi Sidda, Ganesh Arram
Format:	Article
Language:	English
Published:	Serbian Chemical Society 2015-01-01
Series:	Journal of the Serbian Chemical Society
Subjects:	coumarin chalcones Michael addition microwave irradiation pyrazolines
Online Access:	http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391400101A.pdf

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record_format	Article
spelling	doaj-996c5c0a62144fe8a72bf3bc05a568772020-11-25T01:47:48ZengSerbian Chemical Society Journal of the Serbian Chemical Society0352-51391820-74212015-01-0180330531310.2298/JSC140021101A0352-51391400101AMicrowave assisted synthesis of some new coumarin-pyrazoline hybrids and their antimicrobial activityAshok Dongamanti0Lakshmi Bommidi Vijaya1Ravi Sidda2Ganesh Arram3Osmania University, Department of Chemistry, Hyderabad, IndiaOsmania University, Department of Chemistry, Hyderabad, IndiaOsmania University, Department of Chemistry, Hyderabad, IndiaOsmania University, Department of Chemistry, Hyderabad, IndiaA series of pyrazolines 4a-g have been synthesized by Michael addition of chalcones 3a-g with hydrazine hydrate in presence of sodium acetate under conventional heating and microwave irradiation. Structures of the newly synthesized chalcones 3a-g and pyrazolines 4a-g have been established on the basis of IR, 1H & 13C NMR and mass spectral data. All the synthesized compounds were screened for their antimicrobial activity. Some of the compounds shown very good activity compared to standard drugs against all pathogenic bacteria and fungi.http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391400101A.pdfcoumarinchalconesMichael additionmicrowave irradiationpyrazolines
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Ashok Dongamanti Lakshmi Bommidi Vijaya Ravi Sidda Ganesh Arram
spellingShingle	Ashok Dongamanti Lakshmi Bommidi Vijaya Ravi Sidda Ganesh Arram Microwave assisted synthesis of some new coumarin-pyrazoline hybrids and their antimicrobial activity Journal of the Serbian Chemical Society coumarin chalcones Michael addition microwave irradiation pyrazolines
author_facet	Ashok Dongamanti Lakshmi Bommidi Vijaya Ravi Sidda Ganesh Arram
author_sort	Ashok Dongamanti
title	Microwave assisted synthesis of some new coumarin-pyrazoline hybrids and their antimicrobial activity
title_short	Microwave assisted synthesis of some new coumarin-pyrazoline hybrids and their antimicrobial activity
title_full	Microwave assisted synthesis of some new coumarin-pyrazoline hybrids and their antimicrobial activity
title_fullStr	Microwave assisted synthesis of some new coumarin-pyrazoline hybrids and their antimicrobial activity
title_full_unstemmed	Microwave assisted synthesis of some new coumarin-pyrazoline hybrids and their antimicrobial activity
title_sort	microwave assisted synthesis of some new coumarin-pyrazoline hybrids and their antimicrobial activity
publisher	Serbian Chemical Society
series	Journal of the Serbian Chemical Society
issn	0352-5139 1820-7421
publishDate	2015-01-01
description	A series of pyrazolines 4a-g have been synthesized by Michael addition of chalcones 3a-g with hydrazine hydrate in presence of sodium acetate under conventional heating and microwave irradiation. Structures of the newly synthesized chalcones 3a-g and pyrazolines 4a-g have been established on the basis of IR, 1H & 13C NMR and mass spectral data. All the synthesized compounds were screened for their antimicrobial activity. Some of the compounds shown very good activity compared to standard drugs against all pathogenic bacteria and fungi.
topic	coumarin chalcones Michael addition microwave irradiation pyrazolines
url	http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391400101A.pdf
work_keys_str_mv	AT ashokdongamanti microwaveassistedsynthesisofsomenewcoumarinpyrazolinehybridsandtheirantimicrobialactivity AT lakshmibommidivijaya microwaveassistedsynthesisofsomenewcoumarinpyrazolinehybridsandtheirantimicrobialactivity AT ravisidda microwaveassistedsynthesisofsomenewcoumarinpyrazolinehybridsandtheirantimicrobialactivity AT ganesharram microwaveassistedsynthesisofsomenewcoumarinpyrazolinehybridsandtheirantimicrobialactivity
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Microwave assisted synthesis of some new coumarin-pyrazoline hybrids and their antimicrobial activity

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