Identification of Key Genes and Pathways in Persistent Hyperplastic Primary Vitreous of the Eye Using Bioinformatic Analysis

Identification of Key Genes and Pathways in Persistent Hyperplastic Primary Vitreous of the Eye Using Bioinformatic Analysis

Background: The failure of the embryonic hyaloid vascular system to regress naturally causes persistent hyperplastic primary vitreous (PHPV), a congenital eye disease. PHPVs molecular pathway, candidate genes, and drug targets are unknown. The current paper describes a comprehensive analysis using b...

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Bibliographic Details
Main Authors: Derin M. Thomas, Chitra Kannabiran, D. Balasubramanian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Medicine
Subjects:
persistent hyperplastic primary vitreous
gene ontology
bioinformatic analysis
hub genes
molecular pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.690594/full

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