In Vivo Differentiation Potential of Epiblast Stem Cells Revealed by Chimeric Embryo Formation

Chimera formation after blastocyst injection or morula aggregation is the principal functional assay of the developmental potential of mouse embryonic stem cells (ESCs). This property, which demonstrates functional equivalence between ESCs and the preimplantation epiblast, is not shared by epiblast...

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Bibliographic Details
Main Authors: Yali Huang, Rodrigo Osorno, Anestis Tsakiridis, Valerie Wilson
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712003774