In Vivo Differentiation Potential of Epiblast Stem Cells Revealed by Chimeric Embryo Formation
Chimera formation after blastocyst injection or morula aggregation is the principal functional assay of the developmental potential of mouse embryonic stem cells (ESCs). This property, which demonstrates functional equivalence between ESCs and the preimplantation epiblast, is not shared by epiblast...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-12-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124712003774 |