<it>EPHB2 </it>germline variants in patients with colorectal cancer or hyperplastic polyposis

<it>EPHB2 </it>germline variants in patients with colorectal cancer or hyperplastic polyposis

<p>Abstract</p> <p>Background</p> <p><it>Ephrin receptor B2 </it>(<it>EPHB2</it>) has recently been proposed as a novel tumor suppressor gene in colorectal cancer (CRC). Inactivation of the gene has been shown to correlate with progression of col...

Full description

Bibliographic Details
Main Authors:	Schleutker Johanna, Eng Charis, Mecklin Jukka-Pekka, Järvinen Heikki, Carvajal-Carmona Luis G, Korja Sanna, Lehtonen Rainer, Laiho Päivi, Kokko Antti, Tomlinson Ian PM, Vahteristo Pia, Aaltonen Lauri A
Format:	Article
Language:	English
Published:	BMC 2006-06-01
Series:	BMC Cancer
Online Access:	http://www.biomedcentral.com/1471-2407/6/145

Similar Items

Hyperplastic polyposis: a case report
by: Thiago Almeida Flauzino, et al.
Published: (2015-01-01)

Association of hyperplastic polyposis syndrome, colorectal cancer and meningioma
by: Mahvish Muzaffar, et al.
Published: (2011-07-01)

Hyperplastic polyposis, serrated polyps and their relationship to colorectal cancer
by: Lockett, Melanie Jane
Published: (2005)

Colorectal cancer in hyperplastic polyposis syndrome: In search of the polyp of origin
by: Rosty Christophe, et al.
Published: (2011-03-01)

Hyperplastic polyposis syndrome: a call for broader diagnostic criteria
by: Kalady Matthew F, et al.
Published: (2010-05-01)

Germline EPHB2 receptor variants in familial colorectal cancer.
by: George Zogopoulos, et al.
Published: (2008-08-01)

Hyperplastic polyposis syndrome: endoscopic imaging, phenotypic charcteristics and molecular pathways
by: Boparai KS, et al.
Published: (2012-04-01)

Hyperplastic Gastric Polyposis Complicated by a High-Grade Sarcomatoid Malignancy
by: Hugh J Freeman, et al.
Published: (2014-01-01)

Hyperplastic Polyps and Serrated Adenomas in Hereditary Non-Polyposis Colorectal Cancer
by: Speake, Douglas
Published: (2009)

Numbers of mutations to different types of colorectal cancer
by: Tavaré Simon, et al.
Published: (2005-10-01)

Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci
by: Houlston Richard S, et al.
Published: (2011-02-01)

Investigating the potential role of genetic and epigenetic variation of DNA methyltransferase genes in hyperplastic polyposis syndrome.
by: Musa Drini, et al.
Published: (2011-02-01)

Germline mutation at codon 1309 of the adenomatous polyposis coli gene and exteracolonic manifestations in familial adenomatous polyposis
by: Faegheh Behboudi Farahbakhsh, et al.
Published: (2017-07-01)

Hyperplastic Polyposis following Treatment of Gastric Vascular Ectasia: A Case Report and Review of Clinical Correlates
by: M. Ghabril, et al.
Published: (2007-08-01)

Birt-Hogg-Dubé syndrome with simultaneous hyperplastic polyposis of the gastrointestinal tract: case report and review of the literature
by: Flávia Balsamo, et al.
Published: (2020-03-01)

Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results
by: Alisa Olkinuora, et al.
Published: (2020-07-01)

Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome.
by: Mark Clendenning, et al.
Published: (2013-01-01)

A truncated protein product of the germline variant of the DUOX2 gene leads to adenomatous polyposis
by: Mengyuan Yang, et al.
Published: (2021-02-01)

A neoepitope derived from a novel germline Adenomatous polyposis coli (APC) gene mutation in Familial Adenomatous Polyposis (FAP) shows selective immunogenicity
by: Snigdha Majumder, et al.
Published: (2017-12-01)

A distinct APC pathogenic germline variant identified in a southern Thai family with familial adenomatous polyposis
by: Worrawit Wanitsuwan, et al.
Published: (2021-03-01)

Notch signaling promotes serrated neoplasia pathway in colorectal cancer through epigenetic modification of EPHB2 and EPHB4
by: Lian H, et al.
Published: (2018-11-01)

Gastrointestinal polyposis and PTEN mutations: an under-acknowledged diagnostic criterion
by: Heald Brandie, et al.
Published: (2010-05-01)

Mechanisms for EPHB4 regulated contact repulsion
by: Marston, Daniel John
Published: (2004)

EphB signalling in rat prostate development
by: Ashley, George Russell
Published: (2010)

Structure of the EphB6 receptor ectodomain.
by: Emilia O Mason, et al.
Published: (2021-01-01)

The differential expression of EphB2 and EphB4 receptor kinases in normal bladder and in transitional cell carcinoma of the bladder.
by: Xiuqing Li, et al.
Published: (2014-01-01)

Hyperplastic candidiases on dorsum of tongue
by: B G Chenna Keshava, et al.
Published: (2016-01-01)

Hyperplastic Polyps and Gastroduodenal Pseudomelanosis
by: Akanksha Agrawal, et al.
Published: (2017-01-01)

Persistent hyperplastic primary vitreous
by: Consul Sidharth, et al.
Published: (1982-01-01)

Hyperplastic Cardiac Sarcoma Recurrence
by: Masood A. Shariff, et al.
Published: (2015-01-01)

Germline and Somatic Whole-Exome Sequencing Identifies New Candidate Genes Involved in Familial Predisposition to Serrated Polyposis Syndrome
by: Yasmin Soares de Lima, et al.
Published: (2021-02-01)

PCR-based genotyping assays to detect germline APC variant associated with hereditary gastrointestinal polyposis in Jack Russell terriers
by: Kyoko Yoshizaki, et al.
Published: (2021-01-01)

Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis
by: Pilar Mur, et al.
Published: (2018-02-01)

The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β-Catenin/TCF Regulated Transcription
by: Wael M. Abdel-Rahman, et al.
Published: (2016-01-01)

Dysbiosis-Associated Polyposis of the Colon—Cap Polyposis
by: Kazuki Okamoto, et al.
Published: (2018-05-01)

Eleven candidate susceptibility genes for common familial colorectal cancer.
by: Alexandra E Gylfe, et al.
Published: (2013-01-01)

Identification of 5 novel germline <it>APC </it>mutations and characterization of clinical phenotypes in Japanese patients with classical and attenuated familial adenomatous polyposis
by: Mori Hiroki, et al.
Published: (2010-11-01)

Upregulation of Oxytocin Receptor in the Hyperplastic Prostate
by: Zhuo Li, et al.
Published: (2018-08-01)

Bilateral persistent hyperplastic primary vitreous
by: Jain Tarun
Published: (2009-01-01)

Reactive Hyperplastic Lesions of the Oral Cavity
by: Hamideh Kadeh, et al.
Published: (2015-03-01)