Role of Soluble Innate Effector Molecules in Pulmonary Defense against Fungal Pathogens

Role of Soluble Innate Effector Molecules in Pulmonary Defense against Fungal Pathogens

Fungal infections of the lung are life-threatening but rarely occur in healthy, immunocompetent individuals, indicating efficient clearance by pulmonary defense mechanisms. Upon inhalation, fungi will first encounter the airway surface liquid which contains several soluble effector molecules that fo...

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Bibliographic Details
Main Authors: Soledad R. Ordonez, Edwin J. A. Veldhuizen, Martin van Eijk, Henk P. Haagsman
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Microbiology
Subjects:
antimicrobial peptides
pulmonary collectin
lung defense
innate immunity
antifungal defenses
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02098/full

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