Antipsychotic Drugs Reverse MK801-Inhibited Cell Migration and F-actin Condensation by Modulating the Rho Signaling Pathway in B35 Cells

Background and Aim. MK801-induced psychotic symptoms and also the Ras homolog family member A (RhoA) expression and cell division control protein 42 (cdc42) mRNA modulation in the rat brain have been investigated. Antipsychotic drugs (APDs) have been reported to induce Rho GDP-dissociation inhibitor...

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Bibliographic Details
Main Authors: Yi-Chyan Chen, Fu-Ming Tsai, Mao-Liang Chen
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2020/4163274