LEDGF/p75 has increased expression in blasts from chemotherapy-resistant human acute myelogenic leukemia patients and protects leukemia cells from apoptosis <it>in vitro</it>

LEDGF/p75 has increased expression in blasts from chemotherapy-resistant human acute myelogenic leukemia patients and protects leukemia cells from apoptosis <it>in vitro</it>

<p>Abstract</p> <p>Background</p> <p>Relapse due to chemoresistant residual disease is a major cause of death in acute myelogenous leukemia (AML). The present study was undertaken to elucidate the molecular mechanisms of chemoresistance by comparing differential gene ex...

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Bibliographic Details
Main Authors: Pendino Frederic, Gjertsen Bjørn, Kjarland Endre, Myklebust Line M, Huang Tien-sheng, Bruserud Øystein, Døskeland Stein, Lillehaug Johan R
Format: Article
Language:English
Published: BMC 2007-04-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/6/1/31

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http://www.molecular-cancer.com/content/6/1/31

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