Estrogen exacerbates mammary involution through neutrophil-dependent and -independent mechanism

Estrogen exacerbates mammary involution through neutrophil-dependent and -independent mechanism

There is strong evidence that the pro-inflammatory microenvironment during post-partum mammary involution promotes parity-associated breast cancer. Estrogen exposure during mammary involution drives tumor growth through neutrophils’ activity. However, how estrogen and neutrophils influence mammary i...

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Bibliographic Details
Main Authors: Chew Leng Lim, Yu Zuan Or, Zoe Ong, Hwa Hwa Chung, Hirohito Hayashi, Smeeta Shrestha, Shunsuke Chiba, Feng Lin, Valerie Chun Ling Lin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-07-01
Series:eLife
Subjects:
Estrogen
neutrophils
mammary involution
Online Access:https://elifesciences.org/articles/57274

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