Effect of wet mass on dextromethorphan hydrobromide matrix pellets
Dextromethorphan hydrobromide (DM) sustained release matrix pellets containing 10% w/w drug were prepared by an extrusion/spheronization technique. The effect of mixing different concentrations of ethyl cellulose (EC), hydroxypropyl methylcellulpse (HPMC K10), and Carbopol 934 with Avicel PH101 on t...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Universidade de São Paulo
2019-04-01
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Series: | Brazilian Journal of Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000400604&lng=en&tlng=en |