Ubiquitin-Like Modifier Activating Enzyme 1 as a Novel Diagnostic and Prognostic Indicator That Correlates With Ferroptosis and the Malignant Phenotypes of Liver Cancer Cells

Ubiquitin-Like Modifier Activating Enzyme 1 as a Novel Diagnostic and Prognostic Indicator That Correlates With Ferroptosis and the Malignant Phenotypes of Liver Cancer Cells

PurposeFerroptosis is a type of cell death that is iron dependent, a characteristic that distinguishes it from necrosis, apoptosis, and autophagy. However, the ferroptotic mechanisms for hepatitis B virus-associated hepatocellular carcinoma (HCC) remain incompletely described.MethodsTwo hepatitis B...

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Bibliographic Details
Main Authors: Yiru Shan, Guang Yang, Haixia Huang, Yehan Zhou, Xiangyu Hu, Qiuhong Lu, Peng Guo, Jun Hou, Li Cao, Fuhua Tian, Qi Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
ferroptosis
hepatocellular carcinoma
UBA1
Nrf2 signal transduction pathway
weighted gene coexpression network analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.592413/full

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