Developing Placebos for Clinical Research in Traditional Chinese Medicine: Assessing Organoleptic Properties of Three Dosage Forms (Oral Liquid, Capsule and Granule)

Developing Placebos for Clinical Research in Traditional Chinese Medicine: Assessing Organoleptic Properties of Three Dosage Forms (Oral Liquid, Capsule and Granule)

Background: The successful application of randomized, double-blind placebo-controlled studies requires maximum blinding. Organoleptic properties of the placebo should be similar to the drug, making it difficult to distinguish between the two. The uniqueness of traditional Chinese medicine (TCM) prep...

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Bibliographic Details
Main Authors: Mengli Xiao, Jiake Ying, Yang Zhao, Qingna Li, Yingpan Zhao, Rui Gao, Fang Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
traditional Chinese medicine
placebo
simulation effect
evaluation
organoleptic properties
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.673729/full

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