Methotrexate-induced changes in the concentration of antibodies to modified citrulnated vimentin in blood serum of patients with rheumatoid arthritis

Aim. To study effects of methotrexate on the titer of antibodies to mutated citrullinated vimentin (anti-MCV) and ascertain possibility of using this marker for control of treatment results and choice of individual effective dose of the drug. Material and methods. A 12-month trial included 76 patien...

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Main Authors: Natal'ya Petrovna Shilkina, Mariya Sergeevna Voronina, Aleksey Alekseevich Vinogradov, Ol'ga L'vovna Borisova, N P Shilkina, M S Voronina, A A Vinogradov, O L Borisova
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2011-05-01
Series:Терапевтический архив
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Online Access:https://ter-arkhiv.ru/0040-3660/article/view/30824