The Different Functional Distribution of “Not Effector” T Cells (Treg/Tnull) in Colorectal Cancer

The Different Functional Distribution of “Not Effector” T Cells (Treg/Tnull) in Colorectal Cancer

Colorectal cancer (CRC) is the third most common cancer worldwide, ranking as high as the second leading cause of cancer-related deaths in industrialized countries. Consistent with immunosurveillance theory, the immune system is crucial to protect the host from developing tumors, and the major playe...

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Bibliographic Details
Main Authors: Elena Niccolai, Federica Ricci, Edda Russo, Giulia Nannini, Giacomo Emmi, Antonio Taddei, Maria Novella Ringressi, Filippo Melli, Manouela Miloeva, Fabio Cianchi, Paolo Bechi, Domenico Prisco, Amedeo Amedei
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
colorectal cancer
tumor-infiltrating lymphocytes
regulatory T cells
not effector T cells
T helper
tumor microenvironment
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01900/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01900/full

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