Epigallocatechin gallate & curcumin prevent transforming growth factor beta 1-induced epithelial to mesenchymal transition in ARPE-19 cells

Epigallocatechin gallate & curcumin prevent transforming growth factor beta 1-induced epithelial to mesenchymal transition in ARPE-19 cells

Background & objectives: Proliferative vitreoretinopathy (PVR) is characterized by the presence of epiretinal membrane (ERM), which exerts traction and detaches the retina. Epithelial to mesenchymal transition (EMT) of the retinal pigment epithelial (RPE) cells underlies ERM formation. Adjuvant...

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Bibliographic Details
Main Authors: Sivasankar Shanmuganathan, Venil N Sumantran, Narayanasamy Angayarkanni
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Indian Journal of Medical Research
Subjects:
Curcumin - epigallocatechin gallate - epithelial to mesenchymal transition - lycopene - proliferative vitreoretinopathy - Smad-3 - transforming growth factor beta 1
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2017;volume=146;issue=8;spage=85;epage=96;aulast=Shanmuganathan

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