Culture and Real-time Polymerase Chain reaction sensitivity in the diagnosis of invasive meningococcal disease: Does culture miss less severe cases?

Culture and Real-time Polymerase Chain reaction sensitivity in the diagnosis of invasive meningococcal disease: Does culture miss less severe cases?

<h4>Background</h4>Invasive meningococcal disease (IMD) is a highly lethal disease. Diagnosis is commonly performed by culture or Realtime-PCR (qPCR).<h4>Aims</h4>Our aim was to evaluate, retrospectively, whether culture positivity correlates with higher bacterial load and fa...

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Bibliographic Details
Main Authors: Sara Guiducci, Maria Moriondo, Francesco Nieddu, Silvia Ricci, Elisa De Vitis, Arianna Casini, Giovanni Maria Poggi, Giuseppe Indolfi, Massimo Resti, Chiara Azzari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212922

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