High prolidase levels in patients with Familial Mediterranean Fever (FMF)

Introduction. Familial Mediterranean Fever (FMF) is an autoinflammatory disease. Prolidase is a specific imidodipeptidase that plays a role in collagen degradation, and an important role in inflammation and wound healing. Hypoxia-inducible factor-1α (HIF-1) is an important protein in the regulation...

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Main Authors: Bayram Meliha, Derin Mehmet Emin, Doğan Halef Okan, Asan Gökmen, Şahin Mehtap, Şahin Ali
Format: Article
Language:English
Published: Sciendo 2020-03-01
Series:Romanian Journal of Internal Medicine
Subjects:
Online Access:https://doi.org/10.2478/rjim-2019-0025
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spelling doaj-98e7534477b84281b72958f71533abc12021-09-05T14:01:26ZengSciendoRomanian Journal of Internal Medicine2501-062X2020-03-01581273310.2478/rjim-2019-0025rjim-2019-0025High prolidase levels in patients with Familial Mediterranean Fever (FMF)Bayram Meliha0Derin Mehmet Emin1Doğan Halef Okan2Asan Gökmen3Şahin Mehtap4Şahin Ali5Department of Internal Medicine, Cumhuriyet University, Faculty of Medicine, Sivas, TurkeyDepartment of Internal Medicine – Rheumatology, Cumhuriyet University, Faculty of Medicine, Sivas, TurkeyDepartment of Biochemistry, Cumhuriyet University, Faculty of Medicine, Sivas, TurkeyDepartment of Internal Medicine, Cumhuriyet University, Faculty of Medicine, Sivas, TurkeyDepartment of Biochemistry, Cumhuriyet University, Faculty of Medicine, Sivas, TurkeyDepartment of Internal Medicine – Rheumatology, Cumhuriyet University, Faculty of Medicine, Sivas, TurkeyIntroduction. Familial Mediterranean Fever (FMF) is an autoinflammatory disease. Prolidase is a specific imidodipeptidase that plays a role in collagen degradation, and an important role in inflammation and wound healing. Hypoxia-inducible factor-1α (HIF-1) is an important protein in the regulation of immunological response, hemostasis, vascularization. The aim of the study was to compare serum prolidase and HIF-1α levels in patients with FMF in attack-free period and healthy control group.https://doi.org/10.2478/rjim-2019-0025familial mediterranean fever (fmf)prolidasehif-1α
collection DOAJ
language English
format Article
sources DOAJ
author Bayram Meliha
Derin Mehmet Emin
Doğan Halef Okan
Asan Gökmen
Şahin Mehtap
Şahin Ali
spellingShingle Bayram Meliha
Derin Mehmet Emin
Doğan Halef Okan
Asan Gökmen
Şahin Mehtap
Şahin Ali
High prolidase levels in patients with Familial Mediterranean Fever (FMF)
Romanian Journal of Internal Medicine
familial mediterranean fever (fmf)
prolidase
hif-1α
author_facet Bayram Meliha
Derin Mehmet Emin
Doğan Halef Okan
Asan Gökmen
Şahin Mehtap
Şahin Ali
author_sort Bayram Meliha
title High prolidase levels in patients with Familial Mediterranean Fever (FMF)
title_short High prolidase levels in patients with Familial Mediterranean Fever (FMF)
title_full High prolidase levels in patients with Familial Mediterranean Fever (FMF)
title_fullStr High prolidase levels in patients with Familial Mediterranean Fever (FMF)
title_full_unstemmed High prolidase levels in patients with Familial Mediterranean Fever (FMF)
title_sort high prolidase levels in patients with familial mediterranean fever (fmf)
publisher Sciendo
series Romanian Journal of Internal Medicine
issn 2501-062X
publishDate 2020-03-01
description Introduction. Familial Mediterranean Fever (FMF) is an autoinflammatory disease. Prolidase is a specific imidodipeptidase that plays a role in collagen degradation, and an important role in inflammation and wound healing. Hypoxia-inducible factor-1α (HIF-1) is an important protein in the regulation of immunological response, hemostasis, vascularization. The aim of the study was to compare serum prolidase and HIF-1α levels in patients with FMF in attack-free period and healthy control group.
topic familial mediterranean fever (fmf)
prolidase
hif-1α
url https://doi.org/10.2478/rjim-2019-0025
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