Antimicrobial efficacy of synthetic and natural-derived novel endodontic irrigating solution – An In vitro study

• Main Authors: Thangi Sowjanya, Sudhakar Naidu, Mahendra Varma Nadimpalli, Gowtam Dev Dondapati, T B V G Raju, Parvathaneni Krishna Prasad
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2020-01-01
• Series: Journal of International Clinical Dental Research Organization
• Subjects: enterococcus faecalis; peracetic acid; phytic acid; sodium hypochlorite
• Online Access: http://www.jicdro.org/article.asp?issn=2231-0754;year=2020;volume=12;issue=1;spage=21;epage=26;aulast=Sowjanya
• ISSN: 2231-0754

Aim and Objective: This in vitro study was designed to comparatively evaluate the antimicrobial efficacy of peracetic acid (PAA – 0.5% and 1%), phytic acid (IP6 – 0.5% and 1%), and sodium hypochlorite (NaOCl – 3% and 5.25%) as irrigating agents against Enterococcus faecalis. Materials and Methods: Agar plates were prepared using Mueller-Hinton (MH) agar. E. faecalis injected in nutrient broth at 37°C. Well diffusion methods were used to derive results. Plates were inoculated for 36 h at 37°C, and microbial zones of inhibition were recorded. Statistical analysis was performed with repeated measures of analysis of variance. Results: PAA (1%) and IP6 (1%) showed larger zones of microbial inhibition. PAA (0.5%) was statistically significant (P < 0.05) when compared to NaOCl (3% and 5.25%). Conclusion: PAA (1%) was used as an irrigating agent in endodontic failure cases.