Epigenetic Regulation in Mesenchymal Stem Cell Aging and Differentiation and Osteoporosis

Mesenchymal stem cells (MSCs) are a reliable source for cell-based regenerative medicine owing to their multipotency and biological functions. However, aging-induced systemic homeostasis disorders in vivo and cell culture passaging in vitro induce a functional decline of MSCs, switching MSCs to a se...

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Bibliographic Details
Main Authors: Ruoxi Wang, Yu Wang, Lisha Zhu, Yan Liu, Weiran Li
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2020/8836258