Phosphorylation of STAT-1 serine 727 is prolonged in HLA-B27-expressing human monocytic cells.

Phosphorylation of STAT-1 serine 727 is prolonged in HLA-B27-expressing human monocytic cells.

A tissue antigen, HLA-B27, is strongly associated with a group of rheumatic diseases called spondyloarthritides. Despite the intensive research, the exact role of HLA-B27 in the pathogenesis of these diseases is still unclear. Here we studied whether HLA-B27 modulates the phosphorylation of signal t...

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Bibliographic Details
Main Authors: Marja Ruuska, Anna S Sahlberg, Kaisa Granfors, Markus A Penttinen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3549911?pdf=render

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