EFFICACY AND SAFETY OF TOCILIZUMAB IN CHILDREN WITH SYSTEMIC JUVENILE ARTHRITIS IN CLINICAL PRACTICE
The paper presents the results of a prospective trial of the efficiency and safety of tocilizumab (TCZ) therapy for sys- temic juvenile arthritis. It analyzes the impact of factors, such as age at onset of the disease, its duration at the time of TCZ therapy initiation, the number of systemic manif...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IMA-PRESS LLC
2015-04-01
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| Series: | Научно-практическая ревматология |
| Subjects: | |
| Online Access: | https://rsp.mediar-press.net/rsp/article/view/2077 |
| Summary: | The paper presents the results of a prospective trial of the efficiency and safety of tocilizumab (TCZ) therapy for sys- temic juvenile arthritis. It analyzes the impact of factors, such as age at onset of the disease, its duration at the time of TCZ therapy initiation, the number of systemic manifestations, activity of arthritis, and previous experience in using other biological agents, on the efficiency of the therapy. Moreover, the safety of long-term TCZ usage, reasons for dis- continuation of the therapy, its resumption possibilities, and ways of enhancing therapeutic effectiveness are analyzed. |
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| ISSN: | 1995-4484 1995-4492 |