Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer

Abstract This phase II clinical trial was performed to determine whether reduced-port laparoscopic surgery with complete D2 lymph node (LN) dissection for gastric cancer is a safe and feasible surgical technique. The prospectively enrolled 65 gastric cancer patients underwent reduced-port surgery (i...

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Main Authors: Sung Eun Oh, Jeong Eun Seo, Ji Yeong An, Min-Gew Choi, Tae Sung Sohn, Jae Moon Bae, Sung Kim, Jun Ho Lee
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83386-8
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spelling doaj-98c2ed66419f491783624fd25292d5c32021-02-14T12:36:29ZengNature Publishing GroupScientific Reports2045-23222021-02-011111710.1038/s41598-021-83386-8Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancerSung Eun Oh0Jeong Eun Seo1Ji Yeong An2Min-Gew Choi3Tae Sung Sohn4Jae Moon Bae5Sung Kim6Jun Ho Lee7Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineAbstract This phase II clinical trial was performed to determine whether reduced-port laparoscopic surgery with complete D2 lymph node (LN) dissection for gastric cancer is a safe and feasible surgical technique. The prospectively enrolled 65 gastric cancer patients underwent reduced-port surgery (i.e., triple-incision totally laparoscopic distal gastrectomy [Duet TLDG] with D2 lymphadenectomy). Compliance rate was the primary outcome, which was defined as cases in which there was no more than one missing LN station during D2 LN dissection. The secondary outcomes were the numbers of dissected and retrieved LNs in each station and other short-term surgical outcomes and postoperative course. The compliance rate was 58.5%. The total number of retrieved LNs was 41 (range: 14–83 LNs). The most common station missing from LN retrieval was station no. 5 (35/65; 53.8%), followed by station no. 1 (24/65; 36.9%). The overall postoperative complication rate was 20.0% (13/65). One patient underwent surgical treatment for postoperative complications. There was no instances of mortality. Duet TLDG is an oncologically and technically safe surgical method of gastrectomy and D2 lymphadenectomy.https://doi.org/10.1038/s41598-021-83386-8
collection DOAJ
language English
format Article
sources DOAJ
author Sung Eun Oh
Jeong Eun Seo
Ji Yeong An
Min-Gew Choi
Tae Sung Sohn
Jae Moon Bae
Sung Kim
Jun Ho Lee
spellingShingle Sung Eun Oh
Jeong Eun Seo
Ji Yeong An
Min-Gew Choi
Tae Sung Sohn
Jae Moon Bae
Sung Kim
Jun Ho Lee
Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
Scientific Reports
author_facet Sung Eun Oh
Jeong Eun Seo
Ji Yeong An
Min-Gew Choi
Tae Sung Sohn
Jae Moon Bae
Sung Kim
Jun Ho Lee
author_sort Sung Eun Oh
title Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
title_short Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
title_full Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
title_fullStr Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
title_full_unstemmed Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
title_sort compliance with d2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
publisher Nature Publishing Group
series Scientific Reports
issn 2045-2322
publishDate 2021-02-01
description Abstract This phase II clinical trial was performed to determine whether reduced-port laparoscopic surgery with complete D2 lymph node (LN) dissection for gastric cancer is a safe and feasible surgical technique. The prospectively enrolled 65 gastric cancer patients underwent reduced-port surgery (i.e., triple-incision totally laparoscopic distal gastrectomy [Duet TLDG] with D2 lymphadenectomy). Compliance rate was the primary outcome, which was defined as cases in which there was no more than one missing LN station during D2 LN dissection. The secondary outcomes were the numbers of dissected and retrieved LNs in each station and other short-term surgical outcomes and postoperative course. The compliance rate was 58.5%. The total number of retrieved LNs was 41 (range: 14–83 LNs). The most common station missing from LN retrieval was station no. 5 (35/65; 53.8%), followed by station no. 1 (24/65; 36.9%). The overall postoperative complication rate was 20.0% (13/65). One patient underwent surgical treatment for postoperative complications. There was no instances of mortality. Duet TLDG is an oncologically and technically safe surgical method of gastrectomy and D2 lymphadenectomy.
url https://doi.org/10.1038/s41598-021-83386-8
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