Effects of Nonsteroidal Anti-Inflammatory Drugs on Transforming Growth Factor-β Expression and Bioactivity in Rat Osteoblast-Enriched Cultures

Nonsteroidal anti-inflammatory drugs (NSAIDs) have been reported to suppress bone remodeling in normal and repaired bones. Our previous results indicated that ketorolac and indomethacin suppressed proliferation, stimulated early differentiation, and induced apoptosis in cultured osteoblasts. Transfo...

Full description

Bibliographic Details
Main Authors: Je-Ken Chang, Gwo-Jaw Wang
Format: Article
Language:English
Published: Wiley 2003-06-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X09704747