Biomaterials Meet Microfluidics: From Synthesis Technologies to Biological Applications

Microfluidics is characterized by laminar flow at micro-scale dimension, high surface to volume ratio, and markedly improved heat/mass transfer. In addition, together with advantages of large-scale integration and flexible manipulation, microfluidic technology has been rapidly developed as one of th...

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Main Authors: Jingyun Ma, Yachen Wang, Jing Liu
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/8/8/255
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spelling doaj-98b1823a7b0e41fd8915700d8484df632020-11-25T00:03:30ZengMDPI AGMicromachines2072-666X2017-08-018825510.3390/mi8080255mi8080255Biomaterials Meet Microfluidics: From Synthesis Technologies to Biological ApplicationsJingyun Ma0Yachen Wang1Jing Liu2Regenerative Medicine Center, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, ChinaRegenerative Medicine Center, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, ChinaRegenerative Medicine Center, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, ChinaMicrofluidics is characterized by laminar flow at micro-scale dimension, high surface to volume ratio, and markedly improved heat/mass transfer. In addition, together with advantages of large-scale integration and flexible manipulation, microfluidic technology has been rapidly developed as one of the most important platforms in the field of functional biomaterial synthesis. Compared to biomaterials assisted by conventional strategies, functional biomaterials synthesized by microfluidics are with superior properties and performances, due to their controllable morphology and composition, which have shown great advantages and potential in the field of biomedicine, biosensing, and tissue engineering. Take the significance of microfluidic engineered biomaterials into consideration; this review highlights the microfluidic synthesis technologies and biomedical applications of materials. We divide microfluidic based biomaterials into four kinds. According to the material dimensionality, it includes: 0D (particulate materials), 1D (fibrous materials), 2D (sheet materials), and 3D (construct forms of materials). In particular, micro/nano-particles and micro/nano-fibers are introduced respectively. This classification standard could include all of the microfluidic biomaterials, and we envision introducing a comprehensive and overall evaluation and presentation of microfluidic based biomaterials and their applications.https://www.mdpi.com/2072-666X/8/8/255functional biomaterialsmicrofluidicscontrollable synthesisbiological applications
collection DOAJ
language English
format Article
sources DOAJ
author Jingyun Ma
Yachen Wang
Jing Liu
spellingShingle Jingyun Ma
Yachen Wang
Jing Liu
Biomaterials Meet Microfluidics: From Synthesis Technologies to Biological Applications
Micromachines
functional biomaterials
microfluidics
controllable synthesis
biological applications
author_facet Jingyun Ma
Yachen Wang
Jing Liu
author_sort Jingyun Ma
title Biomaterials Meet Microfluidics: From Synthesis Technologies to Biological Applications
title_short Biomaterials Meet Microfluidics: From Synthesis Technologies to Biological Applications
title_full Biomaterials Meet Microfluidics: From Synthesis Technologies to Biological Applications
title_fullStr Biomaterials Meet Microfluidics: From Synthesis Technologies to Biological Applications
title_full_unstemmed Biomaterials Meet Microfluidics: From Synthesis Technologies to Biological Applications
title_sort biomaterials meet microfluidics: from synthesis technologies to biological applications
publisher MDPI AG
series Micromachines
issn 2072-666X
publishDate 2017-08-01
description Microfluidics is characterized by laminar flow at micro-scale dimension, high surface to volume ratio, and markedly improved heat/mass transfer. In addition, together with advantages of large-scale integration and flexible manipulation, microfluidic technology has been rapidly developed as one of the most important platforms in the field of functional biomaterial synthesis. Compared to biomaterials assisted by conventional strategies, functional biomaterials synthesized by microfluidics are with superior properties and performances, due to their controllable morphology and composition, which have shown great advantages and potential in the field of biomedicine, biosensing, and tissue engineering. Take the significance of microfluidic engineered biomaterials into consideration; this review highlights the microfluidic synthesis technologies and biomedical applications of materials. We divide microfluidic based biomaterials into four kinds. According to the material dimensionality, it includes: 0D (particulate materials), 1D (fibrous materials), 2D (sheet materials), and 3D (construct forms of materials). In particular, micro/nano-particles and micro/nano-fibers are introduced respectively. This classification standard could include all of the microfluidic biomaterials, and we envision introducing a comprehensive and overall evaluation and presentation of microfluidic based biomaterials and their applications.
topic functional biomaterials
microfluidics
controllable synthesis
biological applications
url https://www.mdpi.com/2072-666X/8/8/255
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AT yachenwang biomaterialsmeetmicrofluidicsfromsynthesistechnologiestobiologicalapplications
AT jingliu biomaterialsmeetmicrofluidicsfromsynthesistechnologiestobiologicalapplications
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