Untargeted Metabolomic Analysis of the Effects and Mechanism of Nuciferine Treatment on Rats With Nonalcoholic Fatty Liver Disease

Untargeted Metabolomic Analysis of the Effects and Mechanism of Nuciferine Treatment on Rats With Nonalcoholic Fatty Liver Disease

Metabolomic analysis has been used to characterize the effects and mechanisms of drugs for nonalcoholic fatty liver disease (NAFLD) at the metabolic level. Nuciferine is an active component derived from folium nelumbinis and has been demonstrated to have beneficial effects on a high-fat diet (HFD) i...

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Bibliographic Details
Main Authors: Huantian Cui, Yuting Li, Min Cao, Jiabao Liao, Xiangguo Liu, Jing Miao, Hui Fu, Ruiwen Song, Weibo Wen, Zhaiyi Zhang, Hongwu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
nonalcoholic fatty liver disease
nuciferine
metabolic disorder
metabolomic analysis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00858/full

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