Myelin Damage and Repair in Pathologic CNS: Challenges and Prospects

Myelin Damage and Repair in Pathologic CNS: Challenges and Prospects

Injury to the central nervous system (CNS) results in oligodendrocyte cell death and progressive demyelination. Demyelinated axons undergo considerable physiological changes and molecular reorganizations that collectively result in axonal dysfunction, degeneration and loss of sensory and motor funct...

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Bibliographic Details
Main Authors: Arsalan eAlizadeh, Scott M. Dyck, Soheila eKarimi-Abdolrezaee
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Astrocytes
Demyelinating Diseases
Neural Stem Cells
cell therapy
spinal cord injury
demyelination
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00035/full

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