Potential of D-cycloserine in the treatment of behavioral and neuroinflammatory disorders in Parkinson's disease and studies that need to be performed before clinical trials

Potential of D-cycloserine in the treatment of behavioral and neuroinflammatory disorders in Parkinson's disease and studies that need to be performed before clinical trials

Hyperactivation of glutamatergic N-methyl-D-aspartate (NMDA) receptors has been implicated in the excitotoxicity and pathophysiology of Parkinson's disease (PD). NMDA receptor blockers have been used clinically to treat dementia, but their efficacy is controversial. Modulation of NMDA receptors...

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Bibliographic Details
Main Authors: Cornelius Rainer Pawlak, Fu-Shih Chen, Fu-Ying Wu, Ying-Jui Ho
Format: Article
Language:English
Published: Wiley 2012-08-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
COX-2
D-cycloserine
Dementia
Neuroinflammation
Parkinson's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X1200040X

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