Redirection of metabolic flux in Shewanella oneidensis MR-1 by CRISPRi and modular design for 5-aminolevulinic acid production

Redirection of metabolic flux in Shewanella oneidensis MR-1 by CRISPRi and modular design for 5-aminolevulinic acid production

Abstract Programming non-canonical organisms is more attractive due to the prospect of high-value chemical production. Among all, Shewanella oneidensis MR-1 possesses outstanding heme synthesis ability and is well-known for electron transfer, thus has high potential in microbial fuel cell and biorem...

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Bibliographic Details
Main Authors: Ying-Chen Yi, I-Son Ng
Format: Article
Language:English
Published: SpringerOpen 2021-02-01
Series:Bioresources and Bioprocessing
Subjects:
Shewanella oneidensis MR-1
CRISPRi
5-Aminolevulinic acid
Metabolic flux
Heme synthesis
C4 pathway
Online Access:https://doi.org/10.1186/s40643-021-00366-6

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