Chirality Induction in Bioorganometallic Conjugates

Considerable attention has been given to the research field of bioorganometallic chemistry, which is a hybrid chemistry field between biology and organometallic chemistry. The introduction of biomolecules, which have hydrogen bonding sites and chiral centers, into organometallic compounds is a promi...

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Bibliographic Details
Main Authors: Toshiyuki Moriuchi, Satoshi D. Ohmura, Takayo Moriuchi-Kawakami
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Inorganics
Subjects:
Online Access:http://www.mdpi.com/2304-6740/6/4/111
Description
Summary:Considerable attention has been given to the research field of bioorganometallic chemistry, which is a hybrid chemistry field between biology and organometallic chemistry. The introduction of biomolecules, which have hydrogen bonding sites and chiral centers, into organometallic compounds is a promising strategy to construct chirality-organized bioorganometallic conjugates. This feature paper sketches an outline of induction of helical chirality into bioorganometallic conjugates by the control of a torsional twist of the organometallic moiety. Topics covered included control of the helical chirality of 1,n′-disubstituted ferrocene moieties in ferrocene-dipeptide conjugates, and the chirality induction of the Au(I)–Au(I) axis in the dinuclear organogold(I)-uracil conjugates.
ISSN:2304-6740