Neurite outgrowth stimulation by n-3 and n-6 PUFAs of phospholipids in apoE-containing lipoproteins secreted from glial cells

Neurite outgrowth stimulation by n-3 and n-6 PUFAs of phospholipids in apoE-containing lipoproteins secreted from glial cells

PUFAs, which account for 25–30% of the total fatty acids in the human brain, are important for normal brain development and cognitive function. However, it remains unclear how PUFAs are delivered to neurons and exert their effects. In this study, we demonstrated that n-3 and n-6 PUFAs added to the m...

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Bibliographic Details
Main Authors: Mitsuhiro Nakato, Michinori Matsuo, Nozomu Kono, Makoto Arita, Hiroyuki Arai, Jun Ogawa, Noriyuki Kioka, Kazumitsu Ueda
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Journal of Lipid Research
Subjects:
polyunsaturated fatty acid
apolipoprotein E-containing lipoprotein
neuron
apolipoprotein E
low density lipoprotein receptor-related protein 1
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520309640

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http://www.sciencedirect.com/science/article/pii/S0022227520309640

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