Chemoresistance and cancer-related inflammation: Two hallmarks of cancer connected by an atypical link, PKCζ

Chemoresistance and cancer-related inflammation: Two hallmarks of cancer connected by an atypical link, PKCζ

Atypical protein kinase C isoforms are serine threonine kinases involved in various pathological conditions. In recent years, the PKCζ isoform has emerged as an important regulator of multiple cellular processes operating in cancer. In this review, we will focus on the PKCζ isoform as an oxidative-s...

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Bibliographic Details
Main Authors: Alessandro eRimessi, Simone ePatergnani, Elli eIoannidi, Paolo ePinton
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Oncology
Subjects:
Apoptosis
Inflammation
Oxidative Stress
Cancer
chemoresistance
nucleus
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00232/full

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