Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports

Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports

In two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course. In both cases, sIL-2R levels were high before treatment and normalized with the therapeutic effects of chemotherapy, coinciding with the chan...

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Main Authors: Hiroki Yabe, Hironori Ueno, Kensuke Ochi, Hideo Morioka, Hiroo Yabe, Chihiro Terai
Format: Article
Language:English
Published: Karger Publishers 2011-03-01
Series:Case Reports in Oncology
Subjects:
Primary bone lymphoma
PBL
Soluble interleukin-2 receptor
sIL-2R
Tumor marker
Online Access:http://www.karger.com/Article/FullText/325399
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spelling doaj-984f359d48034fb5bbb376bb062cbfc52020-11-24T23:25:22ZengKarger PublishersCase Reports in Oncology1662-65752011-03-014112513110.1159/000325399325399Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case ReportsHiroki YabeHironori UenoKensuke OchiHideo MoriokaHiroo YabeChihiro TeraiIn two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course. In both cases, sIL-2R levels were high before treatment and normalized with the therapeutic effects of chemotherapy, coinciding with the changes in lactate dehydrogenase levels and radiographic findings. Adding to the recently reported results of the diagnostic ability of sIL-2R in PBL, our case study highlights the clinical significance of serum sIL-2R levels as a tumor marker in PBL cases.http://www.karger.com/Article/FullText/325399Primary bone lymphomaPBLSoluble interleukin-2 receptorsIL-2RTumor marker
collection DOAJ
language English
format Article
sources DOAJ
author Hiroki Yabe
Hironori Ueno
Kensuke Ochi
Hideo Morioka
Hiroo Yabe
Chihiro Terai
spellingShingle Hiroki Yabe
Hironori Ueno
Kensuke Ochi
Hideo Morioka
Hiroo Yabe
Chihiro Terai
Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports
Case Reports in Oncology
Primary bone lymphoma
PBL
Soluble interleukin-2 receptor
sIL-2R
Tumor marker
author_facet Hiroki Yabe
Hironori Ueno
Kensuke Ochi
Hideo Morioka
Hiroo Yabe
Chihiro Terai
author_sort Hiroki Yabe
title Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports
title_short Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports
title_full Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports
title_fullStr Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports
title_full_unstemmed Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports
title_sort possible clinical significance of serum soluble interleukin-2 receptor level in primary bone lymphoma: two case reports
publisher Karger Publishers
series Case Reports in Oncology
issn 1662-6575
publishDate 2011-03-01
description In two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course. In both cases, sIL-2R levels were high before treatment and normalized with the therapeutic effects of chemotherapy, coinciding with the changes in lactate dehydrogenase levels and radiographic findings. Adding to the recently reported results of the diagnostic ability of sIL-2R in PBL, our case study highlights the clinical significance of serum sIL-2R levels as a tumor marker in PBL cases.
topic Primary bone lymphoma
PBL
Soluble interleukin-2 receptor
sIL-2R
Tumor marker
url http://www.karger.com/Article/FullText/325399
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AT hironoriueno possibleclinicalsignificanceofserumsolubleinterleukin2receptorlevelinprimarybonelymphomatwocasereports
AT kensukeochi possibleclinicalsignificanceofserumsolubleinterleukin2receptorlevelinprimarybonelymphomatwocasereports
AT hideomorioka possibleclinicalsignificanceofserumsolubleinterleukin2receptorlevelinprimarybonelymphomatwocasereports
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