Predicting lithium treatment response in bipolar patients using gender-specific gene expression biomarkers and machine learning [version 3; referees: 1 approved, 2 approved with reservations]

Background: We sought to test the hypothesis that transcriptome-level gene signatures are differentially expressed between male and female bipolar patients, prior to lithium treatment, in a patient cohort who later were clinically classified as lithium treatment responders. Methods: Gene expression...

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Bibliographic Details
Main Authors: Andy R. Eugene, Jolanta Masiak, Beata Eugene
Format: Article
Language:English
Published: F1000 Research Ltd 2018-12-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-474/v3

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