Qiang Xin 1 Formula Suppresses Excessive Pro-Inflammatory Cytokine Responses and Microglia Activation to Prevent Cognitive Impairment and Emotional Dysfunctions in Experimental Sepsis

Qiang Xin 1 Formula Suppresses Excessive Pro-Inflammatory Cytokine Responses and Microglia Activation to Prevent Cognitive Impairment and Emotional Dysfunctions in Experimental Sepsis

Sepsis commonly leads to acute and long-term cognitive and affective impairments which are associated with increased mortality in patients. Neuroinflammation characterized by excessive cytokine release and immune cell activation underlies the behavioral changes associated with sepsis. We previously...

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Bibliographic Details
Main Authors: Xuerui Wang, Xiaolong Xu, Yuhong Guo, Po Huang, Yanxiang Ha, Rui Zhang, Yunjing Bai, Xuran Cui, Shasha He, Qingquan Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
sepsis
cognitive impairment
emotional dysfunctions
traditional Chinese medicine
neuroinflammation
microglia
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00579/full

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