Complement Genetic Variants and FH Desialylation in S. pneumoniae-Haemolytic Uraemic Syndrome

Complement Genetic Variants and FH Desialylation in S. pneumoniae-Haemolytic Uraemic Syndrome

Haemolytic Uraemic Syndrome associated with Streptococcus pneumoniae infections (SP-HUS) is a clinically well-known entity that generally affects infants, and could have a worse prognosis than HUS associated to E. coli infections. It has been assumed that complement genetic variants associated with...

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Bibliographic Details
Main Authors: Irene Gómez Delgado, Fernando Corvillo, Pilar Nozal, Emilia Arjona, Álvaro Madrid, Marta Melgosa, Juan Bravo, Ágnes Szilágyi, Dorottya Csuka, Nóra Veszeli, Zoltán Prohászka, Pilar Sánchez-Corral
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
factor H
Streptococcus pneumoniae (pneumococcus)
Haemolytic Uraemic Syndrome
genetic variant
complement system
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.641656/full

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